What is Needed for a Consistent and Clinically Effective PRP?

Platelet rich plasma is a complex composition of cellular components.  If samples are prepared properly, a single injection of prp can be used to heal and repair a host of injuries and conditions.  Platelet rich plasma is a biologic, and it is the foundation of autologous biologics and regenerative medicine therapies used in modern medicine.  Platelets contain alpha granules that are full of growth factors.  These growth factors are key to the proliferative repair of damaged tissue. Growth factors stimulate cellular growth, differentiation, proliferation and healing.

Multiple scientific studies done by individual different groups including Marx, Giusti, Kevy and others provide proof of bone and soft tissue healing enhancement with a minimum PRP platelet count of 1,000,000 platelets per microliter.  This translates to a minimum of 1 billion platelets per milliliter.

White blood cell mediators, cytokines and hormones are other cells that are just as important as platelets.  The body sends in these include agranular cell types such as lymphocytes, monocytes, and macrophages to provide a powerful antimicrobial effect.  They bolster the local immune response through the uptake of microbes and particles followed by its digestion and destruction.  They also act as signaling molecules between cells. They bind to specific receptors on the surface of their target cells and attract regenerative cells to it.  These cells are a paramount component of anny PRP and add to its clinical power and potency.